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217 personnes travaillent au LJLL

83 personnels permanents

47 enseignants chercheurs

13 chercheurs CNRS

9 chercheurs INRIA

2 chercheurs CEREMA

12 ingénieurs, techniciens et personnels administratifs

134 personnels non permanents

85 doctorants

16 post-doc et ATER

5 chaires et délégations

12 émérites et collaborateurs bénévoles

16 visiteurs

 

Chiffres janvier 2014

 

Séminaire du LJLL - 30 06 2017 14h00 : Y. Lorenzi

Tommaso Lorenzi (Université de St Andrews)

A partial differential equation approach to studying evolutionary dynamics in cancer cell populations

Résumé
A growing body of evidence supports the idea that solid tumours are complex ecosystems populated by cells with heterogeneous phenotypes, whose dynamics can be described in terms of evolutionary and ecological principles. Under this perspective, it has become increasingly recognised that mathematical modelling can complement experimental cancer research by offering alternative means of interpreting experimental data and by enabling extrapolation beyond empirical observation. This talk deals with mathematical models formulated in terms of partial differential equations which can be used to study evolutionary dynamics in cancer cell populations. In particular, I will present a number of results which illustrate how qualitative analysis and numerical simulation of these equations can help to uncover fresh insights into the critical mechanisms underpinning cancer progression and the emergence of resistance to cytotoxic therapy.